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Olfactory receptor, family 2, subfamily T, member 12
Identifiers
Symbols	OR2T12; OR1-57
External IDs	HomoloGene: 88370
Gene ontology Molecular function: • receptor activity • olfactory receptor activity Cellular component: • membrane • integral to membrane Biological process: • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus
Orthologs
	Human	Mouse
Entrez	127064	n/a
Ensembl	ENSG00000177201	n/a
Uniprot	Q8NG77	n/a
Refseq	NM_001004692 (mRNA) NP_001004692 (protein)	n/a (mRNA) n/a (protein)
Location	Chr 1: 246.52 - 246.53 Mb	n/a
Pubmed search	[1]	n/a

Olfactory receptor, family 2, subfamily T, member 12, also known as OR2T12, is a human gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[1]

See also

• Olfactory receptor

References

Further reading

External links

• MeSH OR2T12+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

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