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Olfactory receptor, family 2, subfamily T, member 4
Identifiers
Symbols OR2T4; OR1-60; OR2T4Q
External IDs MGI3030159 HomoloGene71988
Orthologs
Human Mouse
Entrez 127074 258261
Ensembl ENSG00000196944 ENSMUSG00000060765
Uniprot Q8NH00 n/a
Refseq NM_001004696 (mRNA)
NP_001004696 (protein)
NM_207153 (mRNA)
NP_997036 (protein)
Location Chr 1: 246.59 - 246.59 Mb Chr 11: 58.4 - 58.4 Mb
Pubmed search [1] [2]

Olfactory receptor, family 2, subfamily T, member 4, also known as OR2T4, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

Contents

See also

References

Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052. 

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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