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Olfactory receptor, family 3, subfamily A, member 2
Identifiers
Symbols OR3A2; OLFRA04; OR17-14; OR17-228; OR228
External IDs MGI: 3030244 HomoloGene: 68262
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 4995 258702
Ensembl ENSG00000205813 ENSMUSG00000063116
Uniprot P47893 n/a
Refseq NM_002551 (mRNA)
NP_002542 (protein)		 NM_146707 (mRNA)
NP_666918 (protein)
Location Chr 17: 3.13 - 3.24 Mb Chr 11: 74.15 - 74.15 Mb
Pubmed search [1] [2]

Olfactory receptor, family 3, subfamily A, member 2, also known as OR3A2, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

Contents

See also

References

  1. ^ a b "Entrez Gene: OR3A2 olfactory receptor, family 3, subfamily A, member 2".

Further reading

  • Ben-Arie N, Lancet D, Taylor C, et al. (1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire.". Hum. Mol. Genet. 3 (2): 229–35. PMID 8004088. 
  • Glusman G, Clifton S, Roe B, Lancet D (1997). "Sequence analysis in the olfactory receptor gene cluster on human chromosome 17: recombinatorial events affecting receptor diversity.". Genomics 37 (2): 147–60. doi:10.1006/geno.1996.0536. PMID 8921386. 
  • Rouquier S, Taviaux S, Trask BJ, et al. (1998). "Distribution of olfactory receptor genes in the human genome.". Nat. Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. 
  • Glusman G, Sosinsky A, Ben-Asher E, et al. (2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster.". Genomics 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID 10673334. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052. 

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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v • d • e
G protein-coupled receptors: olfactory receptors
Class I
(fish-like specific receptors)
Family 51
A2 - A4 - A7 - B2 - B4 - B5 - B6 - D1 - E1 - E2 - F1 - F2 - G1 - G2 - H1 - I1 - I2 - L1 - M1 - Q1 - S1 - T1 - V1
Family 52
A1 - A4 - A5 - B2 - B4 - B6 - D1 - E1 - E2 - E4 - E5 - E6 - E8 - H1 - I1 - I2 - J3 - K1 - K2 - L1 - L2 - M1 - N1 - N2 - N4 - N5 - P1 - R1 - W1
Family 56
A1 - A3 - A4 - B1 - B4
Class II
(tetrapod specific receptors)
Family 1
A1 - A2 - B1 - C1 - D2 - D4 - D5 - E1 - E2 - F1 - F2 - G1 - I1 - J1 - J2 - J4 - K1 - L1 - L3 - L4 - L6 - L8 - M1 - N1 - N2 - Q1 - S1 - S2
Family 2
A1 - A2 - A4 - A5 - A7 - A12 - A14 - A25 - A42 - AE1 - AG1 - AG2 - AJ1 - AK2 - AP1 - AT4 - B2 - B3 - B6 - B8 - B11 - C1 - C3 - D2 - D3 - F1 - F2 - G2 - G3 - G6 - H1 - H2 - J1 - J2 - J3 - K2 - L2 - L3 - L5 - L8 - L13 - M2 - M3 - M4 - M5 - M7 - N1P - S2 - T1 - T2 - T3 - T4 - T5 - T6 - T8 - T10 - T11 - T12 - T27 - T29 - T33 - T34 - T35 - V1 - V2 - W1 - W3 - W5 - Y1 - Z1
Family 3
A1 - A2 - A3 - A4
Family 4
A5 - A15 - A16 - A47 - B1 - C3 - C5 - C6 - C11 - C12 - C13 - C15 - C16 - C45 - C46 - D1 - D2 - D5 - D6 - D9 - D10 - D11 - E2 - F3 - F4 - F5 - F6 - F15 - F16 - F17 - F21 - F29 - K1 - K2 - K3 - K5 - K13 - K14 - K15 - K17 - L1 - M1 - M2 - N2 - N4 - N5 - P4 - Q3 - S1 - S2 - X1 - X2
Family 5
A1 - A2 - AC2 - AK2 - AK3 - AN1 - AP2 - AR1 - AS1 - AT1 - AU1 - AY1 - B2 - B3 - B12 - B17 - B21 - BF1 - BU1 - C1 - D13 - D14 - D16 - D18 - F1 - H1 - H2 - H6 - H14 - H15 - I1 - J2 - K1 - K2 - K3 - K4 - L1 - L2 - M1 - M3 - M8 - M9 - M10 - M11 - P2 - P3 - R1 - T1 - T2 - T3 - U1 - V1 - W2
Family 6
A2 - B1 - B2 - B3 - C1 - C2 - C3 - C4 - C6 - C65 - C68 - C70 - C74 - C75 - C76 - F1 - J1 - K2 - K3 - K6 - M1 - N1 - N2 - P1 - Q1 - S1 - T1 - V1 - X1 - Y1
Family 7
A2 - A5 - A10 - A17 - C1 - C2 - D2 - D4 - E24 - G1 - G2 - G3
Family 8
A1 - B2 - B3 - B4 - B8 - B12 - D1 - D2 - D4 - G1 - G2 - G5 - H1 - H2 - H3 - I2 - J1 - J3 - K1 - K3 - K5 - S1 - U1
Family 9
A2 - A4 - G1 - G4 - I1 - K2 - Q1 - Q2
Family 10
A2 - A3 - A4 - A5 - A6 - A7 - AD1 - AG1 - C1 - D4 - G2 - G3 - G4 - G6 - G7 - G8 - G9 - H1 - H2 - H3 - H4 - H5 - J1 - J3 - J5 - J6 - K1 - K2 - P1 - Q1 - R2 - S1 - T2 - V1 - W1 - X1 - Z1
Family 11
A1 - G2 - H1 - H4 - H6 - L1
Family 12
D2 - D3
Family 13
A1 - C2 - C3 - C4 - C5 - C8 - C9 - D1 - F1 - G1 - H1 - J1
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