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Olfactory receptor, family 4, subfamily Q, member 3
Identifiers
Symbols OR4Q3; C14orf13; HSA6; OR14-3; OR4Q4; c14_5008
External IDs MGI3030569 HomoloGene71977
Orthologs
Human Mouse
Entrez 441669 257909
Ensembl n/a ENSMUSG00000046210
Refseq NM_172194 (mRNA)
NP_751944 (protein)
NM_001011754 (mRNA)
NP_001011754 (protein)
Location n/a Chr 14: 49.27 - 49.27 Mb
Pubmed search [1] [2]

Olfactory receptor, family 4, subfamily Q, member 3, also known as OR4Q3, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

Contents

See also

References

Further reading

  • Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. doi:10.1073/pnas.040580197. PMID 10706615. 
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052. 

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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