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Olfactory receptor, family 52, subfamily E, member 4
Identifiers
Symbols	OR52E4; OR11-55
External IDs	MGI: 3030511 HomoloGene: 81596
Gene ontology Molecular function: • receptor activity • olfactory receptor activity Cellular component: • membrane • integral to membrane Biological process: • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus
Orthologs
	Human	Mouse
Entrez	390081	258355
Ensembl	ENSG00000180974	ENSMUSG00000073914
Uniprot	Q8NGH9	n/a
Refseq	NM_001005165 (mRNA) NP_001005165 (protein)	NM_146358 (mRNA) NP_666470 (protein)
Location	Chr 11: 5.86 - 5.86 Mb	Chr 7: 104.93 - 104.93 Mb
Pubmed search	[1]	[2]

Olfactory receptor, family 52, subfamily E, member 4, also known as OR52E4, is a human gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[1]

See also

• Olfactory receptor

References

Further reading

External links

• MeSH OR52E4+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

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