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Olfactory receptor, family 5, subfamily M, member 8
Identifiers
Symbols	OR5M8; OR11-194
External IDs	MGI: 3030865 HomoloGene: 73973
Gene ontology Molecular function: • receptor activity • olfactory receptor activity Cellular component: • membrane • integral to membrane Biological process: • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus
Orthologs
	Human	Mouse
Entrez	219484	257916
Ensembl	ENSG00000181371	ENSMUSG00000043267
Uniprot	Q8NGP6	n/a
Refseq	NM_001005282 (mRNA) NP_001005282 (protein)	NM_001011759 (mRNA) NP_001011759 (protein)
Location	Chr 11: 56.01 - 56.02 Mb	Chr 2: 85.79 - 85.79 Mb
Pubmed search	[1]	[2]

Olfactory receptor, family 5, subfamily M, member 8, also known as OR5M8, is a human gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[1]

See also

• Olfactory receptor

References

Further reading

External links

• MeSH OR5M8+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

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