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Salvia divinorum, a psychedelic sage

Psychedelic plants are plants that contain psychedelic drugs. Some of them have been used for thousands of years for religious purposes.

Contents

Cannabis

Cannabis plant
Main article: Cannabis (drug)

Cannabis (Marijuana) is a popular psychedelic plant. Cannabis is also unique in that it contains a psychedelic substance, THC, which contains no nitrogen and is not an indole, phenethylamine, anticholinergic (deliriant), or a disassociative drug. It is the weakest of the psychedelics. Currently, certain universities and research firms are studying the medicinal effects of cannabis. Many US states such as California and many countries have created a Medical Cannabis law to allow patients to use cannabis as (among other things) a pain killer and appetite stimulant.

Plants containing psychedelic tryptamines

DMT Molecule in 2D
DMT Molecule in 3D

Many of the psychedelic plants contain dimethyltryptamine (DMT), which is either snorted (Virola, Yopo snuffs), smoked, or drunk with MAOIs (Ayahuasca). It can not simply be eaten, and it needs to be extremely concentrated to be smokable, since the user needs to smoke all of it in a minute or else tolerance builds rapidly.

Acanthaceae:

  • Fittonia albivenis, a common ornamental plant from South America. The plant has unknown compounds, that reportedly cause "visions of eyeballs." It is also useful in the treatment of headaches, etc.
  • Justicia pectoralis, DMT in leaves[1]

Aceraceae:

  • Acer saccharinum (Silver Maple Tree) was found to contain the indole alkaloid gramine (not active and extremely toxic) 0.05% in the leaves, so it is possible that other members of this plant family contain active compounds.[2]

Aizoaceae:

Delosperma acuminatum
DMT, 5-MEO-DMT[3]
Delosperma cooperi
DMT, 5-MEO-DMT[3]
Delosperma ecklonis
DMT[3]
Delosperma esterhuyseniae
DMT[3]
Delosperma hallii
5-MEO-DMT[3]
Delosperma harazianum
DMT, 5-MEO-DMT[3]
Delosperma harazianum
Shibam
DMT[3]
Delosperma hirtum
DMT[3]
Delosperma hallii
aff. litorale
Delosperma lydenbergense
DMT, 5-MEO-DMT[3]
Delosperma nubigenum
5-MEO-DMT[3]
Delosperma pageanum
DMT, 5-MEO-DMT[3]
Delosperma pergamentaceum
Traces of DMT[3]
Delosperma tradescantioides
DMT[3]

Apocynaceae family:

Fabaceae family (Leguminosae):

Caesalpinioideae (subfamily of Fabaceae) :

Acacia acuminata
Up to 1.5% alkaloids, mainly consisting of tryptamine in leaf[7]
Acacia alpina
Active principles in leaf[8]
Acacia angustissima
β-methyl-phenethylamine[9], NMT and DMT in leaf (1.1-10.2 ppm)[10]
Acacia aroma
Tryptamine alkaloids.[11] Significant amount of tryptamine in the seeds.[12]
Acacia auriculiformis
5-MeO-DMT in stem bark[13]
Acacia baileyana
0.02% tryptamine and β-carbolines, in the leaf, Tetrahydroharman[8][14][15]
Acacia beauverdiana
Psychoactive[16] Ash used in Pituri.[17]
Acacia berlandieri
DMT, amphetamines, mescaline, nicotine[18]
Acacia catechu
DMT[3] and other tryptamines in leaf, bark
Acacia caven
Psychoactive[19]
Acacia chundra
DMT and other tryptamines in leaf, bark
Acacia colei
DMT[20]
Acacia complanata
0.3% alkaloids in leaf and stem, almost all N-methyl-tetrahydroharman, with traces of tetrahydroharman, some of tryptamine[21][22][23]
Acacia confusa
DMT & NMT in leaf, stem & bark 0.04% NMT and 0.02% DMT in stem.[8] Also N,N-dimethyltryptamine N-oxide[24]
Acacia cornigera
Psychoactive,[19] Tryptamines[25]
Acacia cultriformis
Tryptamine, in the leaf, stem[8] and seeds.[12] Phenethylamine in leaf and seeds[12]
Acacia cuthbertsonii
Psychoactive[16]
Acacia decurrens
Psychoactive,[19] but less than 0.02% alkaloids[15]
Acacia delibrata
Psychoactive[16]
Acacia falcata
Psychoactive,[16] but less than 0.02% alkaloids[15]
Acacia farnesiana
Traces of 5-MeO-DMT[26] in fruit. β-methyl-phenethylamine, flower.[27] Ether extracts about 2-6% of the dried leaf mass.[28] Alkaloids are present in the bark[29] and leaves.[30] Amphetamines and mescaline also found in tree.[25]
Acacia floribunda
Tryptamine, phenethylamine,[31] in flowers[12] other tryptamines,[32] phenethylamines[33]
Acacia georginae
Psychoactive,[19] plus deadly toxins
Acacia horrida
Psychoactive[19]
Acacia implexa
Psychoactive[34]
Acacia jurema
DMT, NMT
Acacia karroo
Psychoactive
Acacia laeta
DMT, in the leaf[8]
Acacia longifolia
0.2% tryptamine in bark, leaves, some in flowers, phenylethylamine in flowers,[31] 0.2% DMT in plant.[35] Histamine alkaloids.[15]
Acacia longifolia
var. sophorae
Tryptamine in leaves, bark[12]
Acacia macradenia
Tryptamine[12]
Acacia maidenii
0.6% NMT and DMT in about a 2:3 ratio in the stem bark, both present in leaves[8]
Acacia mangium
Psychoactive[19]
Acacia melanoxylon
DMT, in the bark and leaf,[36] but less than 0.02% total alkaloids[15]
Acacia mellifera
DMT, in the leaf[8]
Acacia nilotica
DMT, in the leaf[8]
Acacia nilotica
subsp. adstringens
Psychoactive, DMT in the leaf
Acacia obtusifolia
Tryptamine,[32] DMT, NMT, other tryptamines,[34] 0.4-0.5% in dried bark, 0.07% in branch tips.[37]
Acacia oerfota
Less than 0.1% DMT in leaf,[38][14] NMT
Acacia penninervis
Psychoactive[16]
Acacia phlebophylla
0.3% DMT in leaf, NMT[8]
Acacia podalyriaefolia
Tryptamine in the leaf,[8] 0.5% to 2% DMT in fresh bark, phenethylamine, trace amounts[31]
Acacia polyacantha
DMT in leaf[8] and other tryptamines in leaf, bark
Acacia polyacantha
ssp. campylacantha
Less than 0.2% DMT in leaf, NMT; DMT and other tryptamines in leaf, bark[39]
Acacia rigidula
DMT, NMT, tryptamine, traces of amphetamines, mescaline, nicotine and others[40]
Acacia sassa
Psychoactive[19]
Acacia schaffneri
β-methyl-phenethylamine, Phenethylamine[41] Amphetamines and mescaline also found.[25]
Acacia senegal
Less than 0.1% DMT in leaf,[8] NMT, other tryptamines. DMT in plant,[27] DMT in bark.Cite error: Closing </ref> missing for <ref> tag[8]
Acacia tortilis
DMT, NMT, and other tryptamines[34]
Acacia vestita
Tryptamine, in the leaf and stem,[8] but less than 0.02% total alkaloids[15]
Acacia victoriae
Tryptamines[32], 5-MeO-alkyltryptamine[12]

List of Acacia Species Having Little or No Alkaloids in the Material Sampled:[15]

0% \le C \le 0.02%, C...Concentration of Alkaloids [%]

Anadenanthera colubrina
Anadenanthera colubrina var. cebil
Bufotenin and Dimethyltryptamine have been isolated from the seeds and seed pods, 5-MeO-DMT from the bark of the stems.[44] The seeds were found to contain 12.4% bufotenine, 0.06% 5-MeO-DMT and 0.06% DMT.[45]
Anadenanthera peregrina
Anadenanthera peregrina var. peregrina

Bufotenine is in the seeds.[47]

Desmanthus illinoensis
0% - 0.34% DMT in root bark, highly variable.[48] Also NMT, N-hydroxy-N-methyltryptamine, 2-hydroxy-N-methyltryptamine, and gramine (toxic).[49]
Desmanthus leptolobus
0.14% DMT in root bark, more reliable than D. illinoensis[48]
Desmodium caudatum[50]
(syn. Ohwia caudata )
Roots: 0.087% DMT,[51] Bufotenine-N-oxide 0.03%
Desmodium gangeticum
DMT, 5-MEO-DMT, whole plant, roots, stems, leaves[52]
Desmodium intortum
Bufotentine, DMT[53]
Codariocalyx motorius
(syn. Desmodium gyrans)
DMT, 5-MEO-DMT, leaves, roots[52]
Desmodium racemosum
5-MEO-DMT[52]
Desmodium triflorum
0.0004% DMT-N-oxide, roots,[51] less in stems[51] and trace in leaves.[51]
Lespedeza capitata
Lespedeza bicolor
DMT, 5-MEO-DMT in leaves and roots[54]
Lespedeza bicolor var. japonica
DMT, 5-MEO-DMT in leaves and root bark[52]
Mimosa ophthalmocentra
Dried root: DMT 1.6%, NMT 0.0012% and hordenine 0.0065%[55]
Mimosa scabrella
Tryptamine, NMT, DMT and N-methyltetrahydrocarboline in bark[56]
Mimosa somnians
Trytamines and MMT
Mimosa tenuiflora
(syn. "Mimosa hostilis")
0.31-0.57% DMT (dry root bark).[57]
Mimosa verrucosa
DMT[58] in root bark
Mucuna pruriens
"The leaves, seeds, stems and roots contain L-Dopa, Serotonin, 5-HTP, and Nicotine, as well as N,N-DMT, Bufotenine, and 5-MeO-DMT."[59]
Petalostylis casseoides
0.4-0.5% tryptamine, DMT, etc. in leaves and stems[54]
Petalostylis labicheoides var. casseoides
DMT in leaves and stems[52]
Phyllodium pulchellum
(syn. Desmodium pulchellum)
0.2% 5-MeO-DMT, small quantities of DMT[54] DMT (dominates in seedlings and young plants), 5-MEO-DMT (dominates in mature plant), whole plant, roots, stems, leaves, flowers[52]

Family Fabaceae: Erythrina flabelliformis, other Erythrina species, seeds contain the alkaloids Erysodin and Erysovin[60]

Lauraceae:

  • Nectandra megapotamica, NMT[6]

Malpighiaceae family:

Myristicaceae (Nutmeg family):

  • Horsfieldia superba: 5-MeO-DMT[54] and beta-carbolines[5]
  • Iryanthera macrophylla: 5-MeO-DMT in bark[54]
  • Iryanthera ulei: 5-MeO-DMT in bark[52]
  • Osteophloem platyspermum: DMT, 5-MeO-DMT in bark[52]
Virola calophylla Leaves 0.149% DMT, leaves 0.006% MMT[52] 5-MeO-DMT in bark[62]
Virola callophylloidea DMT
Virola carinata DMT in leaves[52]
Virola cuspidata DMT[6]
Virola divergens DMT in leaves[52]
Virola elongata
(syn. Virola theiodora)
DMT, 5-MEO-DMT in bark, roots, leaves and flowers[52]
Virola melinonii DMT in bark[52]
Virola multinervia DMT, 5-MEO-DMT in bark and roots[52]
Virola pavonis DMT in leaves[52]
Virola peruviana 5-MEO-DMT, traces of DMT and 5-MeO-tryptamine in bark[52]
Virola rufula Alkaloids in bark and root, 95% of which is MeO-DMT[63] 0.190% 5-MeO-DMT in bark,[52] 0.135% 5-MeO-DMT in root, 0.092% DMT in leaves.[52]
Virola sebifera The bark contains 0.065% to 0.25% alkaloids, most of which are DMT and 5-MeO-DMT.[64]
Virola surinamensis DMT[6] in bark[52]
Virola venosa DMT, 5-MEO-DMT in roots, leaves[52] DMT

Ochnaceae:

Ochnaceae:

Genus Pandanus (Screw Pine): DMT in nuts[54]

Poaceae family (Gramineae):

Some Graminae (grass) species contain gramine, which can cause brain damage, other organ damage, central nervous system damage and death in sheep.[65]

Species
Alkaloids (Dried)
Arundo donax
0.0057% DMT in dried rhizome, no stem, 0.026% bufotenine, 0.0023% 5-MeO-MMT[66]
Phalaris aquatica
0.0007-0.18% Total alkaloids,[67] 0.100% DMT,[68] 0.022% 5-MeO-DMT,[68]0.005% 5-OH-DMT[68]
Phalaris arundinacea
0.0004-0.121% Total alkaloids[67]
Phalaris brachystachys
Aerial parts up to 3% total alkaloids, DMT present[citation needed]
Phragmites australis
DMT in roots[52]

None of the above alkaloids are said to have been found in Phalaris californica, Phalaris canariensis, Phalaris minor and hybrids of P. arundinacea together with P. aquatica.[67]

Polygonaceae:

  • Erigonum sp.: DMT[52]

Punicaceae:

  • Punica granatum "DMT in root cortex;"[6] The dried stem and root bark of the tree contain about 0.4-0.9% alkaloids.[69]

Rubiaceae family:

Species
Alkaloids (Dried)
Psychotria carthagenensis
0.2% average DMT in dried leaves[52]
Psychotria expansa
DMT[6]
Psychotria forsteriana
DMT[6]
Psychotria insularum
DMT[6]
Psychotria poeppigiana [3]
DMT[6]
Psychotria rostrata
DMT[6]
Psychotria rufipilis
DMT[6]
Psychotria viridis
DMT 0.1-0.61% dried mass.[70]

Rutaceae family:

Species
Alkaloids (Dried)
Dictyoloma incanescens
5-MeO-DMT in leaves,[52][63] 0.04% 5-MeO-DMT in bark[54]
Dutaillyea drupacea
> 0.4 % 5-MeO-DMT in leaves[52][34]
Dutaillyea oreophila
5-MeO-DMT in leaves[52]
Tetradium ruticarpum
(syn. Evodia rutaecarpa)
5-MeO-DMT in leaves,[52] fruit and roots
Limonia acidissima
5-MeO-DMT in stems[52]
Melicope leptococca
0.2% total alkaloids, 0.07% 5-MeO-DMT; 5-MeO-DMT in leaves and stems,[52] also "5-MeO-DMT-Oxide and a beta-carboline"[5]
Pilocarpus organensis
5-MeO-DMT in leaves[52]
Vepris ampody
Up to 0.2% DMT in leaves and branches[52][54]
Zanthoxylum arborescens
DMT in leaves[52]
Zanthoxylum procerum
DMT in leaves[52]

Urticaceae:

  • Urtica pilulifera: Bufotenin[6]

Other Indoles

Acoraceae:

Mescaline

Species
Alkaloid Content (Fresh)
Alkaloid Content (Dried)
Echinopsis lageniformis
(syn. Trichocereus bridgesii)
Mescaline > 0.025%,[71] also 3,4-dimethoxyphenylethylamine < 1%, 3-methoxytyramine < 1%, tyramine < 1%
2%[72]
Echinopsis pachanoi
(syn. Trichocereus pachanoi)
Mescaline 0.006-0.12%, 0.05% Average[73]
Mescaline 0.01%-2.375%[73]
Echinopsis spachiana
(syn. Trichocereus spachianus)
Mescaline[74]
Mescaline[74]
Lophophora williamsii
(Peyote)
0.4% Mescaline[75]
3-6% Mescaline[74]
Opuntia acanthocarpa
Mescaline[74]
Opuntia basilaris
Mescaline 0.01%, plus 4-hydroxy-3-5
-dimethoxyphenethylamine[74]
Austrocylindropuntia cylindrica
(syn. Opuntia cylindrica)[76]
Mescaline[74]
Cylindropuntia echinocarpa
(syn. Opuntia echinocarpa)
Mescaline 0.01%, 3-4-dimethoxyphenethylamine 0.01%, 4-hydroxy-3-5-dimethoxyphenethylamine 0.01%[74]
Cylindropuntia spinosior
(syn. Opuntia spinosior)[77]
Mescaline 0.00004%, 3-methoxytyramine 0.001%, tyramine 0.002%, 3-4-dimethoxyphenethylamine.[74]
Echinopsis macrogona
(syn. Trichocereus macrogonus)
> 0.01-0.05% Mescaline[78]
Echinopsis peruviana
(syn. Trichocereus peruvianus)
Mescaline 0.0005%-0.12%[73]
Mescaline
Echinopsis tacaquirensis
subsp. taquimbalensis
(syn. Trichocereus taquimbalensis)[79]
> 0.005-0.025% Mescaline[78]
Echinopsis terscheckii
(syn. Trichocereus terscheckii, Trichocereus werdemannianus)[80]
> 0.005-0.025% Mescaline[78]
Mescaline 0.01%-2.375%[73]
Echinopsis valida
0.025% Mescaline[75]

Plants containing beta-carbolines

Beta-carbolines are "reversible" MAO-A inhibitors. They are found in some plants used to make Ayahuasca. In high doses the harmala alkaloids are somewhat hallucinogenic on their own.

Apocynaceae:

Amsonia tabernaemontana
Harmine
Aspidosperma exalatum
Beta-carbolines[81]
Aspidosperma polyneuron
Beta-carbolines[81]
Apocynum cannabinum
Harmalol
Ochrosia nakaiana
Harman
Pleicarpa mutica
Beta-carbolines[81]

Bignoniaceae:

  • Newbouldia laevis, Harman

Calycanthaceae:

Calycanthus occidentalis
Harmine

Chenopodiaceae:

  • Hammada leptoclada, Tetrahydroharman, etc.
  • Kochia scoparia, Harmine, etc.

Combretaceae:

  • Guiera senegalensis, Harman, etc.

Cyperaceae:

  • Carex brevicollis, Harmine, etc.
  • Carex parva, Beta-carbolines[81]

Elaeagnaceae:

Elaeagnus angustifolia
Harman, etc.
Elaeagnus commutata
Beta-carbolines[81]
Elaeagnus hortensis
Tetrahydroharman, etc.
Elaeagnus orientalis
Tetrahydroharman
Elaeagnus spinosa
Tetrahydroharman
Hippophae rhammoides
Harman, etc.
Shepherdia argentea
Tetrahydroharmol
Shepherdia canadensis
Tetrahydroharmol

Gramineae:

Arundo donax
Tetrahydroharman
Festuca arundinacea
Harman, etc.
Lolium perenne
(Perennial Ryegrass)
Harman, etc.
Phalaris aquatica
Beta-carbolines[81]
Phalaris arundinacea
Beta-carbolines[81]

Lauraceae:

  • Nectandra megapotamica, Beta-carbolines[81]

Leguminosae:

Loganiaceae:

  • Strychnos melinoniana, Beta-carbolines[81]
  • Strychnos usambarensis, Harman[81]

Malpighiaceae:

Banisteriopsis argentia
5-methoxytetrahydroharman, (-)-N(6)-methoxytetrahydroharman, dimethyltryptamine-N(6)-oxide[9]
Banisteriopsis caapi
Harmine 0.31-8.43%,[82] tetrahydroharmine, telepathine, dihydroshihunine,[83] 5-MeO-DMT in bark[84]
Banisteriopsis inebrians
Beta-carbolines[81]
Banisteriopsis lutea
Harmine, telepathine[9]
Banisteriopsis metallicolor
Harmine, telepathine[9]
Banisteriopsis muricata
Harmine up to 6%, harmaline up to 4%, plus DMT[85]
Diplopterys cabrerana
Beta-carbolines[81]
Cabi pratensis
Beta-carbolines[81]
Callaeum antifebrile
(syn. Cabi paraensis)
Harmine

Myristicaceae:

Ochnaceae:

Palmae:

  • Plectocomiopsis geminiflorus, Beta-carbolines[81]

Papaveraceae:

Meconopsis horridula
Beta-carbolines[81]
Meconopsis napaulensis
Beta-carbolines[81]
Meconopsis panuculata
Beta-carbolines[81]
Meconopsis robusta
Beta-carbolines[81]
Meconopsis rudis
Beta-carbolines[81]
Papaver rhoeas
Beta-carbolines[81]

Passifloraceae:

Passiflora actinea
Harman
Passiflora alata
Harman
Passiflora alba
Harman
Passiflora bryonoides
Harman
Passiflora caerulea
Harman
Passiflora capsularis
Harman
Passiflora decaisneana
Harman
Passiflora edulis
Harman, 0-7001 ppm[27] in fruit
Passiflora eichleriana
Harman
Passiflora foetida
Harman
Passiflora incarnata
(with bee)
Harmine, Harmaline, Harman, etc. 0.03%.[86] Alkaloids in rind of fruit 0.25%[86]
Passiflora quadrangularis
Harman
Passiflora ruberosa
Harman
Passiflora subpeltata
Harman
Passiflora warmingii
Harman

Polygonaceae:

  • Calligonum minimum, Beta-carbolines[81]
  • Leptactinia densiflora, Leptaflorine, etc.
  • Ophiorrhiza japonica, Harman
  • Pauridiantha callicarpoides, Harman
  • Pauridiantha dewevrei, Harman
  • Pauridiantha lyalli, Harman
  • Pauridiantha viridiflora, Harman
  • Simira klugii, Harman
  • Simira rubra, Harman

Rubiaceae:

  • Borreria verticillata, Beta-carbolines[81]
  • Leptactinia densiflora, Beta-carbolines[81]
  • Nauclea diderrichii, Beta-carbolines[81]
  • Ophiorrhiza japonica, Beta-carbolines[81]
  • Pauridiantha callicarpoides, Beta-carbolines[81]
  • Pauridiantha dewevrei, Beta-carbolines[81]
  • Pauridiantha yalli, Beta-carbolines[81]
  • Pauridiantha viridiflora, Beta-carbolines[81]
  • Pavetta lanceolata, Beta-carbolines[81]
  • Psychotria carthagenensis, Beta-carbolines[81]
  • Psychotria viridis, Beta-carbolines[81]
  • Simira klugii, Beta-carbolines[81]
  • Simira rubra, Beta-carbolines[81]
  • Uncaria attenuata, Beta-carbolines[81]
  • Uncaria canescens, Beta-carbolines[81]
  • Uncaria orientalis, Beta-carbolines[81]

Rubiaceae:

Rutaceae family:

  • Tetradium (syn. Evodia) species: Some contain carbolines
  • Melicope leptococca: Beta-carboline[5]
  • Araliopsis tabouensis, Beta-carbolines[81]
  • Findersia laevicarpa, Beta-carbolines[81]
  • Xanthoxylum rhetsa, Beta-carbolines[81]

Sapotaceae:

  • Chrysophyllum lacouritianum, Norharman etc.

Simaroubaceae:

  • Ailanthus malabarica, Beta-carbolines[81]
  • Perriera madagascariensis, Beta-carbolines[81]
  • Picrasma ailanthoides, Beta-carbolines[81]
  • Picrasma crenata, Beta-carbolines[81]
  • Picrasma excelsa, Beta-carbolines[81]
  • Picrasma javanica, Beta-carbolines[81]

Solanaceae:

  • Vestia foetida, (Syn V. lycioides) Beta-carbolines[81]

|Vestia foetida

Tiliaceae:

  • Grewia mollis, Beta-carbolines[81]

Zygophyllaceae: